Ethical Contracting for Clinical Trials

Ethical Considerations in Clinical Trials

Accessible online at: www.karger.com/journals/hed Ethical aspects of biomedical research in humans have been unmasked at a late stage in the history of science. They have been apparent for not more than approximately 60 years, and did not gain attention as a result of ongoing refinements of fundamental human rights. On the contrary, their recognition followed a traditional pattern in the histor...

O-18: Framework of Informed Consent and Ethical Codes for Clinical Trials Especially Designed for Assisted Reproduction

Background Clinical trials are known as the most valid medical research. It is able to promote medical evidences on prevention, diagnosis, screening, treatment, and quality of life because in this type of study, an intervention is intentionally performed on subjects. Therefore, it encompasses ethical concerns and considerations, especially when human subjects are studied. In other words, clinic...

Clinical trials: two neglected ethical issues.

Ethical reasons are presented for requiring 1) that a proposal for a clinical trial should be accompanied by a thorough review of all previous trials that have examined the same and closely related questions, and 2) that a trial should be approved by a research ethics committee only if the investigator undertakes to register it in an appropriate register of clinical trials as soon as one exists.

Clinical trials in neonates: ethical issues.

If neonates are to receive the best possible treatment, they must be involved in clinical trials. However, doing such trials raises complicated ethical issues. These issues are not unique to neonatology but some are more common or acute than in other areas of medicine. In practice, two particular issues -- equipoise and informed consent -- arise as many different types of problem. The question ...

Ethical and legal aspects of clinical trials.